Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person SHC1, phosphorylated by NTRK3 (TRKC), binds GRB2. Based on s...

Class:IdSummation:9036954
_displayNameSHC1, phosphorylated by NTRK3 (TRKC), binds GRB2. Based on s...
_timestamp2018-02-14 17:49:44
created[InstanceEdit:9036953] Orlic-Milacic, Marija, 2018-02-14
literatureReference[LiteratureReference:9034894] Analysis of mitogen-activated protein kinase activation by naturally occurring splice variants of TrkC, the receptor for neurotrophin-3
modified[InstanceEdit:9036967] Orlic-Milacic, Marija, 2018-02-14
textSHC1, phosphorylated by NTRK3 (TRKC), binds GRB2. Based on studies of NTRK1 (TRKA) and NTRK2 (TRKB2) and evidence that RAS signaling is activated downstream of NTRK3 (Gunn-Moore et al. 1997, Yuen and Mobley 1999), GRB2 is shown in complex with RAS guanine nucleotide exchange factor SOS1.
(summation)[BlackBoxEvent:9036949] NTRK3 binds GRB2:SOS1 through SHC1 [Homo sapiens]
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