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Query author contributions in Reactome

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Details on Person Endonuclease-exonuclease-phosphatase family domain containin...

Class:IdSummation:9035195
_displayNameEndonuclease-exonuclease-phosphatase family domain containin...
_timestamp2019-08-14 04:18:08
created[InstanceEdit:9035177] Shamovsky, Veronica, 2018-01-18
literatureReference[LiteratureReference:9035144] EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux
[LiteratureReference:9035131] Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells
modified[InstanceEdit:9616765] Shamovsky, Veronica, 2018-08-14
[InstanceEdit:9619547] Shamovsky, Veronica, 2018-09-18
[InstanceEdit:9629273] Shamovsky, Veronica, 2018-11-20
[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03
[InstanceEdit:9658354] Shamovsky, Veronica, 2019-08-13
[InstanceEdit:9658427] Shamovsky, Veronica, 2019-08-14
textEndonuclease-exonuclease-phosphatase family domain containing 1 (EEPD1/KIAA1706) was identiified as a direct transcriptional target of liver X receptors (LXR alpha (NR1H3) and LXR beta (NR1H2)) in murine bone marrow-derived macrophages (BMDM), J774 macrophages and in human monocyte-like THP-1 cells (Nelson JK et al. 2017). An LXR alpha (NR1H3) ChIP-seq study identified a LXR-response element (LXRE) in intron 2 of EEPD1 gene (Nelson JK et al. 2017; Feldmann R et al. 2013).
(summation)[Reaction:9035167] NR1H2,3 binds the EEPD1 gene [Homo sapiens]
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