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Details on Person TYSND1 cleaves HSD17B4

Class:Id	Reaction:9033530
_displayName	TYSND1 cleaves HSD17B4
_doRelease	TRUE
_timestamp	2018-03-12 07:49:08
authored	[InstanceEdit:9033487] May, Bruce, 2017-12-22
catalystActivity	[CatalystActivity:9033507] serine-type endopeptidase activity of TYSND1 [peroxisomal matrix]
catalystActivityReference	[CatalystActivityReference:9643902] serine-type endopeptidase activity of TYSND1 [peroxisomal matrix] Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrix
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:9033525] May, Bruce, 2017-12-22
edited	[InstanceEdit:9033487] May, Bruce, 2017-12-22
inferredFrom	[Reaction:9034351] Tysnd1 cleaves Hsd17b4 [Mus musculus]
input	[EntityWithAccessionedSequence:192322] HSD17B4(1-736) [peroxisomal matrix] [Homo sapiens] [SimpleEntity:141343] H2O [peroxisomal matrix]
isChimeric	FALSE
literatureReference	[LiteratureReference:9033508] Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrix [LiteratureReference:389983] Structure of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein [LiteratureReference:193363] Peroxisomal multifunctional protein-2: the enzyme, the patients and the knockout mouse model
modified	[InstanceEdit:9034380] May, Bruce, 2018-01-04 [InstanceEdit:9036907] May, Bruce, 2018-02-13 [InstanceEdit:9036919] May, Bruce, 2018-02-13 [InstanceEdit:9038630] May, Bruce, 2018-03-12 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TYSND1 cleaves HSD17B4
output	[EntityWithAccessionedSequence:9033503] HSD17B4(1-311) [peroxisomal matrix] [Homo sapiens] [EntityWithAccessionedSequence:9033495] HSD17B4(312-736) [peroxisomal matrix] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9033235] Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix [Homo sapiens] [Reaction:9033236] PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) [Homo sapiens]
releaseDate	2018-03-18
reviewed	[InstanceEdit:9036917] Fransen, Marc, 2018-02-13 [InstanceEdit:9036916] Van Veldhoven, Paul P, 2018-02-13 [InstanceEdit:9038621] Azevedo, Jorge E, 2018-03-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9033571] R-HSA-9033530.4
summation	[Summation:9034347] The trypsin-like serine-type endopeptidase TYSND1 cleaves HS...
(hasEvent)	[Pathway:9033500] TYSND1 cleaves peroxisomal proteins [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779457] Update Tracker - [Reaction:9033530] TYSND1 cleaves HSD17B4 - v65:[modifyText]
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No pathways have been reviewed or authored by TYSND1 cleaves HSD17B4 (9033530)