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Details on Person PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)

Class:Id	Reaction:9033238
_displayName	PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
_doRelease	TRUE
_timestamp	2018-03-12 07:46:14
authored	[InstanceEdit:9033239] May, Bruce, 2017-12-18
compartment	[Compartment:17947] peroxisomal membrane
created	[InstanceEdit:9033234] May, Bruce, 2017-12-19
edited	[InstanceEdit:9033239] May, Bruce, 2017-12-18
inferredFrom	[Reaction:9033857] Pex14 binds PEX5L (in PEX5L:PEX7:Acaa1a) [Cricetulus griseus]
input	[Complex:9033606] PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] [Homo sapiens] [Complex:9033115] PEX5L:PEX7:Cargo protein [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9033082] Revisiting the intraperoxisomal pathway of mammalian PEX7 [LiteratureReference:9033005] A PEX7-centered perspective on the peroxisomal targeting signal type 2-mediated protein import pathway [LiteratureReference:9033609] Domain mapping of human PEX5 reveals functional and structural similarities to Saccharomyces cerevisiae Pex18p and Pex21p [LiteratureReference:9033043] Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import [LiteratureReference:9033833] Identification and characterization of the human orthologue of yeast Pex14p [LiteratureReference:9036563] Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor
modified	[InstanceEdit:9033626] May, Bruce, 2017-12-23 [InstanceEdit:9033892] May, Bruce, 2017-12-28 [InstanceEdit:9036576] May, Bruce, 2018-02-05 [InstanceEdit:9036919] May, Bruce, 2018-02-13 [InstanceEdit:9038630] May, Bruce, 2018-03-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module)
output	[Complex:9033117] PEX5L:PEX7:Cargo:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] [Homo sapiens]
precedingEvent	[Reaction:9033240] PEX5L binds PEX7:Cargo protein [Homo sapiens] [Reaction:9033232] PEX7 binds cargo proteins containing PTS2 [Homo sapiens]
releaseDate	2018-03-18
reviewed	[InstanceEdit:9036917] Fransen, Marc, 2018-02-13 [InstanceEdit:9036916] Van Veldhoven, Paul P, 2018-02-13 [InstanceEdit:9038621] Azevedo, Jorge E, 2018-03-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9033243] R-HSA-9033238.3
summation	[Summation:9033816] PEX5L bound to PEX7:Cargo interacts with the peroxisomal mem...
(hasEvent)	[Pathway:9033241] Peroxisomal protein import [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9033514] Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779358] Update Tracker - [Reaction:9033238] PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) - v65:[modifyText]
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No pathways have been reviewed or authored by PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (9033238)