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Details on Person The complex of activated NTRK2 (TRKB) and activated FYN bind...

Class:IdSummation:9032584
_displayNameThe complex of activated NTRK2 (TRKB) and activated FYN bind...
_timestamp2017-12-21 17:15:07
created[InstanceEdit:9032585] Orlic-Milacic, Marija, 2017-12-15
literatureReference[LiteratureReference:9032550] Involvement of BDNF receptor TrkB in spatial memory formation
[LiteratureReference:9032649] BDNF Contributes to Spinal Long-Term Potentiation and Mechanical Hypersensitivity Via Fyn-Mediated Phosphorylation of NMDA Receptor GluN2B Subunit at Tyrosine 1472 in Rats Following Spinal Nerve Ligation
modified[InstanceEdit:9032594] Orlic-Milacic, Marija, 2017-12-15
[InstanceEdit:9032597] Orlic-Milacic, Marija, 2017-12-15
[InstanceEdit:9032660] Orlic-Milacic, Marija, 2017-12-15
[InstanceEdit:9032661] Orlic-Milacic, Marija, 2017-12-15
[InstanceEdit:9033475] Orlic-Milacic, Marija, 2017-12-21
textThe complex of activated NTRK2 (TRKB) and activated FYN binds to the NMDA receptor complex subunit GRIN2B (also known as NR2B or GluN2B). The GRIN2A subunit of the NMDA receptor does not co-immunoprecipitate with activated FYN (Mizuno et al. 2003, Li et al. 2017). It is not clear whether FYN interacts with GRIN2B in the context of the NMDA receptor complex.
(summation)[BlackBoxEvent:9032582] Activated FYN binds GRIN2B [Homo sapiens]
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