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Details on Person NTRK2-phosphorylated FRS2 binds GRB2

Class:IdBlackBoxEvent:9032073
_displayNameNTRK2-phosphorylated FRS2 binds GRB2
_doReleaseTRUE
_timestamp2018-02-20 17:56:29
authored[InstanceEdit:9034391] Orlic-Milacic, Marija, 2018-01-05
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:9032072] Orlic-Milacic, Marija, 2017-12-05
edited[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
input[Complex:9031960] BDNF,NTF4:p-5Y-NTRK2:p-Y-FRS2 [plasma membrane] [Homo sapiens]
[Complex:109797] GRB2-1:SOS1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9031570] Brain-derived neurotrophic factor induces phosphorylation of fibroblast growth factor receptor substrate 2
modified[InstanceEdit:9032374] Orlic-Milacic, Marija, 2017-12-12
[InstanceEdit:9032383] Orlic-Milacic, Marija, 2017-12-12
[InstanceEdit:9037702] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9037704] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9037712] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNTRK2-phosphorylated FRS2 binds GRB2
output[Complex:9032071] BDNF,NTF4:p-5Y-NTRK2:p-Y-FRS2:GRB2-1:SOS1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2018-03-21
reviewed[InstanceEdit:9037707] Antila, Hanna, 2018-02-13
[InstanceEdit:9037710] Castrén, Eero, 2018-02-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9032077] R-HSA-9032073.2
summation[Summation:9032382] BDNF treatment induces formation of a complex between FRS2 a...
(hasEvent)[Pathway:9028731] Activated NTRK2 signals through FRS2 and FRS3 [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9032067] NTRK2 activates RAS signaling through FRS2 [Homo sapiens]
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No pathways have been reviewed or authored by NTRK2-phosphorylated FRS2 binds GRB2 (9032073)