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Details on Person Maresin-like SPMs translocate from cytosol to extracellular region

Class:Id	BlackBoxEvent:9031803
_displayName	Maresin-like SPMs translocate from cytosol to extracellular region
_doRelease	TRUE
_timestamp	2025-07-18 16:50:41
authored	[InstanceEdit:9031854] Jassal, Bijay, 2017-12-04
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:9031821] Jassal, Bijay, 2017-12-04
edited	[InstanceEdit:9031854] Jassal, Bijay, 2017-12-04
goBiologicalProcess	[GO_BiologicalProcess:262593] icosanoid secretion
input	[DefinedSet:9031800] Maresin-like SPMs [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9027018] Maresin-like lipid mediators are produced by leukocytes and platelets and rescue reparative function of diabetes-impaired macrophages
modified	[InstanceEdit:9031871] Jassal, Bijay, 2017-12-04 [InstanceEdit:9031876] Jassal, Bijay, 2017-12-04 [InstanceEdit:9037605] Jassal, Bijay, 2018-02-20 [InstanceEdit:9037798] Jassal, Bijay, 2018-02-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9961057] D'Eustachio, Peter, 2025-07-18
name	Maresin-like SPMs translocate from cytosol to extracellular region
output	[DefinedSet:9031809] Maresin-like SPMs [extracellular region]
precedingEvent	[Reaction:9027042] CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 [Homo sapiens] [Reaction:9027033] Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA [Homo sapiens] [Reaction:9027321] CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA [Homo sapiens] [Reaction:9027043] CYPs hydroxylate DHA to 14(R)-HDHA [Homo sapiens] [Reaction:9027302] CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA [Homo sapiens] [Reaction:9027033] Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA [Homo sapiens] [Reaction:9027044] CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 [Homo sapiens] [Reaction:9027043] CYPs hydroxylate DHA to 14(R)-HDHA [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9031840] R-HSA-9031803.3
summation	[Summation:9031874] To produce their pro-resolving effects, maresin-like SPMs (M...
(hasEvent)	[Pathway:9027307] Biosynthesis of maresin-like SPMs [Homo sapiens]
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