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Details on Person NR1H2,3 binds the APOC1 gene

Class:IdReaction:9031518
_displayNameNR1H2,3 binds the APOC1 gene
_doReleaseTRUE
_timestamp2019-08-12 15:58:08
authored[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9031514] Shamovsky, Veronica, 2017-11-30
edited[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input[CandidateSet:9024381] NR1H2,3:RXR [nucleoplasm] [Homo sapiens]
[DefinedSet:9024383] NR1H3, NR1H2 ligands [nucleoplasm]
[EntityWithAccessionedSequence:9031516] APOC1 gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9035126] Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta
modified[InstanceEdit:9035120] Shamovsky, Veronica, 2018-01-18
[InstanceEdit:9607281] Shamovsky, Veronica, 2018-05-01
[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03
[InstanceEdit:9634161] Shamovsky, Veronica, 2019-01-07
[InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19
[InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09
[InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNR1H2,3 binds the APOC1 gene
LXR binds the APOC1 gene
output[Complex:9031523] NR1H2,3:RXR:NR1H2,3 ligand:APOC1 gene [nucleoplasm] [Homo sapiens]
releaseDate2019-09-10
reviewed[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29
[InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9031532] R-HSA-9031518.2
summation[Summation:9607276] Ligand-activated liver X receptors (LXRα, NR1H3 and LXRβ NR1...
(hasEvent)[Pathway:9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9031510] Expression of APOC1 regulated by NR1H2 or NR1H3 [Homo sapiens]
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