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Details on Person BDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1

Class:IdReaction:9030450
_displayNameBDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1
_doReleaseTRUE
_timestamp2018-02-20 17:56:26
authored[InstanceEdit:9034391] Orlic-Milacic, Marija, 2018-01-05
catalystActivity[CatalystActivity:9030455] protein tyrosine kinase activity of BDNF,NTF4:p-5Y-Ntrk2:Plcg1 [plasma membrane]
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:9030454] Orlic-Milacic, Marija, 2017-11-27
edited[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
input[Complex:9030449] BDNF,NTF4:p-5Y-Ntrk2:Plcg1 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
isChimericTRUE
literatureReference[LiteratureReference:9026808] Early BDNF, NT-3, and NT-4 signaling events
modified[InstanceEdit:9030466] Orlic-Milacic, Marija, 2017-11-27
[InstanceEdit:9037702] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9037704] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9037712] Orlic-Milacic, Marija, 2018-02-20
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameBDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1
output[Complex:9030462] BDNF,NTF4:p-5Y-Ntrk2:p-4Y-Plcg1 [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2018-03-21
reviewed[InstanceEdit:9037707] Antila, Hanna, 2018-02-13
[InstanceEdit:9037710] Castrén, Eero, 2018-02-13
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
[Species:48892] Mus musculus
[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:9030457] R-NUL-9030450.2
summation[Summation:9030463] Recombinant rat Ntrk2 (TrkB), activated by recombinant human...
(inferredFrom)[Reaction:9026579] NTRK2 phosphorylates PLCG1 [Homo sapiens]
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No pathways have been reviewed or authored by BDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1 (9030450)