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Details on Person NCOA1 recruits EP300 to the ABCA1 promoter

Class:Id	Reaction:9029561
_displayName	NCOA1 recruits EP300 to the ABCA1 promoter
_doRelease	TRUE
_timestamp	2019-08-12 15:23:44
authored	[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9029533] Shamovsky, Veronica, 2017-11-20
edited	[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input	[EntityWithAccessionedSequence:381325] EP300 [nucleoplasm] [Homo sapiens] [Complex:9029599] NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9029582] Role of p160 coactivator complex in the activation of liver X receptor
modified	[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03 [InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19 [InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09 [InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NCOA1 recruits EP300 to the ABCA1 promoter
output	[Complex:9029520] EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9029551] NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex [Homo sapiens] [Reaction:9024334] Co-repressor complex dissociates from the transcription unit of the ABCA1 gene [Homo sapiens]
releaseDate	2019-09-10
reviewed	[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29 [InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9029620] R-HSA-9029561.2
summation	[Summation:9029539] Activation of liver X receptors LXRα (NR1H3) and LXRβ (NR1H2...
(hasEvent)	[Pathway:9029569] NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux [Homo sapiens]
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No pathways have been reviewed or authored by NCOA1 recruits EP300 to the ABCA1 promoter (9029561)