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Details on Person Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex

Class:IdReaction:9029517
_displayNameOxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex
_doReleaseTRUE
_timestamp2019-08-12 16:00:11
authored[InstanceEdit:9035107] Shamovsky, Veronica, 2018-01-18
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9029533] Shamovsky, Veronica, 2017-11-20
edited[InstanceEdit:9657765] Shamovsky, Veronica, 2019-08-09
input[DefinedSet:9024383] NR1H3, NR1H2 ligands [nucleoplasm]
[Complex:9029554] UGT1A3 gene:NR1H2,3:RXR:NCOR [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9024438] The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice
modified[InstanceEdit:9035222] Shamovsky, Veronica, 2018-01-18
[InstanceEdit:9634037] Shamovsky, Veronica, 2019-01-03
[InstanceEdit:9637777] Shamovsky, Veronica, 2019-02-19
[InstanceEdit:9657834] Shamovsky, Veronica, 2019-08-09
[InstanceEdit:9658282] Shamovsky, Veronica, 2019-08-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameOxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex
Oxysterol binds to the UGT1A3 gene:LXR:RXR:NCOR complex
output[Complex:9029556] UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOR [nucleoplasm] [Homo sapiens]
releaseDate2019-09-10
reviewed[InstanceEdit:9633727] D'Eustachio, Peter, 2018-12-29
[InstanceEdit:9657850] Cummins, Carolyn L, Repa, Joyce J, 2019-08-09
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9029617] R-HSA-9029517.2
summation[Summation:9029540] UDP Glucuronosyltransferase Family 1 Member A3 (UGT1A3) is a...
(hasEvent)[Pathway:9623433] NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis [Homo sapiens]
(precedingEvent)[Reaction:9029566] Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene [Homo sapiens]
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