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Details on Person p-S363,S380,T573 RS6K translocates to the nucleus

Class:Id	BlackBoxEvent:9029434
_displayName	p-S363,S380,T573 RS6K translocates to the nucleus
_doRelease	TRUE
_timestamp	2018-11-08 16:59:47
authored	[InstanceEdit:9027683] Rothfels, Karen, 2017-11-03
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9029433] Rothfels, Karen, 2017-11-17
edited	[InstanceEdit:9027683] Rothfels, Karen, 2017-11-03 [InstanceEdit:9619846] Orlic-Milacic, Marija, 2018-09-18 [InstanceEdit:9628239] Orlic-Milacic, Marija, 2018-11-07
input	[CandidateSet:9619873] p-S221,T359.S363,S380,T573,T732-RSK [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9029421] Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1 [LiteratureReference:9029428] Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo [LiteratureReference:444248] The RSK family of kinases: emerging roles in cellular signalling
modified	[InstanceEdit:9038337] Rothfels, Karen, 2018-02-26 [InstanceEdit:9038487] Rothfels, Karen, 2018-02-27 [InstanceEdit:9619831] Orlic-Milacic, Marija, 2018-09-18 [InstanceEdit:9619834] Orlic-Milacic, Marija, 2018-09-18 [InstanceEdit:9619846] Orlic-Milacic, Marija, 2018-09-18 [InstanceEdit:9619880] Orlic-Milacic, Marija, 2018-09-18 [InstanceEdit:9620038] Orlic-Milacic, Marija, 2018-09-20 [InstanceEdit:9628237] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628240] Orlic-Milacic, Marija, 2018-11-07 [InstanceEdit:9628439] Orlic-Milacic, Marija, 2018-11-08 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-S363,S380,T573 RS6K translocates to the nucleus
output	[CandidateSet:444291] p-S221,T359,S363,S380,T573,T732-RSK [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:442739] PDPK1 phosphorylates RSKs [Homo sapiens] [Reaction:9620004] RSKs autophosphorylate [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9026999] D'Eustachio, Peter, 2017-10-25 [InstanceEdit:9627687] Yi, Feng, 2018-11-02 [InstanceEdit:9628437] Hansen, Kasper B, 2018-11-02
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9029435] R-HSA-9029434.3
summation	[Summation:9029431] Inactive 90 kDa ribosomal S6 kinases (RSKs) can be detected ...
(hasEvent)	[Pathway:444257] RSK activation [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9778906] Update Tracker - [BlackBoxEvent:9029434] p-S363,S380,T573 RS6K translocates to the nucleus - v67:[add_removeInput, add_removeOutput, modifyText]
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