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Query author contributions in Reactome

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Details on Person EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:SOS1

Class:IdReaction:9029149
_displayNameEPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:SOS1
_doReleaseTRUE
_timestamp2018-08-14 15:48:56
authored[InstanceEdit:9029159] May, Bruce, 2017-11-11
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9029161] May, Bruce, 2017-11-14
edited[InstanceEdit:9029159] May, Bruce, 2017-11-11
inferredFrom
input[Complex:9029088] EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1 [plasma membrane] [Homo sapiens]
[Complex:109797] GRB2-1:SOS1 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9029007] The signal transduction through Grb2/Ash in hematopoietic cells
[LiteratureReference:9029077] Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein
modified[InstanceEdit:9030367] May, Bruce, 2017-11-27
[InstanceEdit:9616794] Matthews, Lisa, 2018-08-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:SOS1
output[Complex:9029089] EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1:GRB2:SOS1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2018-09-12
reviewed[InstanceEdit:9616793] McGraw, Kathy L, 2018-08-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9029170] R-HSA-9029149.2
summation[Summation:9030358] Phosphorylated SHC1 in the EPOR complex serves as a scaffold...
(hasEvent)[Pathway:9027284] Erythropoietin activates RAS [Homo sapiens]
(precedingEvent)[Reaction:9029158] EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS [Homo sapiens]
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No pathways have been reviewed or authored by EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:SOS1 (9029149)
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