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Details on Person Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein

Class:Id	LiteratureReference:9029077
_displayName	Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein
_timestamp	2017-11-14 12:54:50
author	[Person:9027146] Damen, J E [Person:68356] Liu, L [Person:9027201] Cutler, R L [Person:9006253] Krystal, G
created	[InstanceEdit:9029065] May, Bruce, 2017-11-14
journal	Blood
pages	2296-303
pubMedIdentifier	8400282
title	Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein
volume	82
year	1993
(literatureReference)	[CatalystActivityReference:9643786] protein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:SHC1 [plasma membrane] Erythropoietin stimulates the tyrosine phosphorylation of Shc and its association with Grb2 and a 145-Kd tyrosine phosphorylated protein [CatalystActivityReference:9643836] protein tyrosine kinase activity of Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:Shc1 [plasma membrane] Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor [Complex:9029089] EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:p-Y-SHC1:GRB2:SOS1 [plasma membrane] [Homo sapiens] [Complex:9029107] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1:Grb2-1:Sos1 [plasma membrane] [Mus musculus] [Reaction:9029146] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1 binds Grb2-1:Sos1 [Mus musculus] [Reaction:9029147] Jak2 phosphorylates Shc1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef:Shc1 [Mus musculus] [Reaction:9029149] EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:SOS1 [Homo sapiens] [Reaction:9029155] JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 [Homo sapiens]
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