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Details on Person ALOX5 oxidises EPA to 5-HEPE

Class:IdReaction:9027628
_displayNameALOX5 oxidises EPA to 5-HEPE
_doReleaseTRUE
_timestamp2018-02-21 13:47:28
authored[InstanceEdit:9027630] Jassal, Bijay, 2017-11-03
catalystActivity[CatalystActivity:9020578] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of ALOX5 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9027630] Jassal, Bijay, 2017-11-03
edited[InstanceEdit:9027630] Jassal, Bijay, 2017-11-03
input[SimpleEntity:2026977] EPA [cytosol]
[SimpleEntity:29368] O2 [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9028212] Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives
[LiteratureReference:9028241] Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils
modified[InstanceEdit:9027643] Jassal, Bijay, 2017-11-03
[InstanceEdit:9028211] Jassal, Bijay, 2017-11-07
[InstanceEdit:9037610] Jassal, Bijay, 2018-02-20
[InstanceEdit:9037803] Jassal, Bijay, 2018-02-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameALOX5 oxidises EPA to 5-HEPE
output[SimpleEntity:9028283] 5-HEPE [cytosol]
releaseDate2018-03-21
reviewed[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9027642] R-HSA-9027628.2
summation[Summation:9028249] In human neutrophils, 5-lipoxygenase (ALOX5) can mediate the...
(hasEvent)[Pathway:9027604] Biosynthesis of electrophilic ω-3 PUFA oxo-derivatives [Homo sapiens]
(precedingEvent)[Reaction:9027632] 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA [Homo sapiens]
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No pathways have been reviewed or authored by ALOX5 oxidises EPA to 5-HEPE (9027628)