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Details on Person Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 binds Plcg1,2

Class:IdReaction:9027436
_displayNameEpo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 binds Plcg1,2
_doReleaseTRUE
_timestamp2018-08-14 15:49:36
authored[InstanceEdit:9027411] May, Bruce, 2017-10-30
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9027378] May, Bruce, 2017-11-01
edited[InstanceEdit:9027411] May, Bruce, 2017-10-30
input[Complex:9006303] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 [plasma membrane] [Mus musculus]
[DefinedSet:9027374] Plcg1,2 [cytosol] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:9027409] Epo-induced erythroid maturation is dependent on PlcĪ³1 signaling
[LiteratureReference:9027412] Erythropoietin receptor Y479 couples to ERK1/2 activation via recruitment of phospholipase Cgamma
[LiteratureReference:9027421] Erythropoietin-modulated calcium influx through TRPC2 is mediated by phospholipase Cgamma and IP3R
[LiteratureReference:9027417] Phosphatidylinositol 3-kinase regulates glycosylphosphatidylinositol hydrolysis through PLC-gamma(2) activation in erythropoietin-stimulated cells
[LiteratureReference:9027372] Erythropoietin induces glycosylphosphatidylinositol hydrolysis. Possible involvement of phospholipase c-gamma(2)
modified[InstanceEdit:9031741] May, Bruce, 2017-12-02
[InstanceEdit:9616794] Matthews, Lisa, 2018-08-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEpo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 binds Plcg1,2
output[Complex:9027420] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:Plcg1,2 [plasma membrane] [Mus musculus]
releaseDate2018-09-12
reviewed[InstanceEdit:9616793] McGraw, Kathy L, 2018-08-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9027437] R-MMU-9027436.2
summation[Summation:9031733] Plcg1 (Phospholipase C gamma1) or Plcg2 binds phosphotyrosin...
(inferredFrom)[Reaction:9027373] EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds PLCgamma [Homo sapiens]
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No pathways have been reviewed or authored by Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 binds Plcg1,2 (9027436)
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