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Details on Person Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line
| Class:Id | LiteratureReference:9027367 |
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| _displayName | Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line |
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| _timestamp | 2017-11-01 09:38:35 |
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| author | [Person:9027430] Ren, H Y
[Person:9015528] Komatsu, N
[Person:9027431] Shimizu, R
[Person:2399502] Okada, K
[Person:2682276] Miura, Y |
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| created | [InstanceEdit:9027378] May, Bruce, 2017-11-01 |
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| journal | J. Biol. Chem. |
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| pages | 19633-8 |
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| pubMedIdentifier | 8034732 |
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| title | Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line |
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| volume | 269 |
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| year | 1994 |
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| (literatureReference) | [Pathway:9027277] Erythropoietin activates Phospholipase C gamma (PLCG) [Homo sapiens]
[Reaction:9027373] EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds PLCgamma [Homo sapiens]
[Reaction:9027425] LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2 [Homo sapiens]
[Reaction:9032478] EPOR-associated PLCG hydrolyzes 1-Phosphatidyl-1D-myo-inositol 4,5-bisphosphate [Homo sapiens]
[CatalystActivityReference:9643864] protein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:PLCG1,2 [plasma membrane] Erythropoietin induces tyrosine phosphorylation and activation of phospholipase C-gamma 1 in a human erythropoietin-dependent cell line |
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