Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 binds SHC1

Class:IdReaction:9027274
_displayNameEPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 binds SHC1
_doReleaseTRUE
_timestamp2018-08-14 15:48:20
authored[InstanceEdit:9027270] May, Bruce, 2017-10-21
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9027279] May, Bruce, 2017-10-29
edited[InstanceEdit:9027270] May, Bruce, 2017-10-21
inferredFrom
input[Complex:9024731] EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:74680] SHC1 [cytosol] [Homo sapiens]
isChimericFALSE
modified[InstanceEdit:9027444] May, Bruce, 2017-11-01
[InstanceEdit:9030367] May, Bruce, 2017-11-27
[InstanceEdit:9616794] Matthews, Lisa, 2018-08-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameEPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 binds SHC1
output[Complex:9027236] EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1:SHC1 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2018-09-12
reviewed[InstanceEdit:9616793] McGraw, Kathy L, 2018-08-14
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9027295] R-HSA-9027274.2
summation[Summation:9030352] After stimulation by EPO, CRKL associates with EPOR, is phos...
(hasEvent)[Pathway:9027284] Erythropoietin activates RAS [Homo sapiens]
(precedingEvent)[Reaction:9029155] JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 [Homo sapiens]
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No pathways have been reviewed or authored by EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 binds SHC1 (9027274)