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Details on Person Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation

Class:Id	LiteratureReference:9027143
_displayName	Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation
_timestamp	2017-10-29 12:05:26
author	[Person:9027200] Verdier, F [Person:5678887] Chr�tien, S [Person:9006160] Billat, C [Person:9027169] Gisselbrecht, S [Person:9006179] Lacombe, C [Person:9006210] Mayeux, P
created	[InstanceEdit:9027089] May, Bruce, 2017-10-29
journal	J. Biol. Chem.
pages	26173-8
pubMedIdentifier	9334184
title	Erythropoietin induces the tyrosine phosphorylation of insulin receptor substrate-2. An alternate pathway for erythropoietin-induced phosphatidylinositol 3-kinase activation
volume	272
year	1997
(literatureReference)	[Complex:9012639] EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-Y-IRS2:PI3K [plasma membrane] [Homo sapiens] [CatalystActivityReference:9643385] protein tyrosine kinase activity of EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2 [plasma membrane] Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation [Reaction:9006325] EPO binds EPOR:JAK2:LYN:IRS2 [Homo sapiens] [Reaction:9006326] Epo binds Epor:Jak2:Lyn:Irs2 [Mus musculus] [Reaction:9027272] EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 [Homo sapiens]
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