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Details on Person Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor

Class:IdLiteratureReference:9027084
_displayNameActivation of the mitogen-activated protein kinase pathway by the erythropoietin receptor
_timestamp2017-10-29 12:03:45
author[Person:2682276] Miura, Y
[Person:6785886] Miura, O
[Person:6785818] Ihle, J N
[Person:9006191] Aoki, N
created[InstanceEdit:9027089] May, Bruce, 2017-10-29
journalJ. Biol. Chem.
pages29962-9
pubMedIdentifier7961995
titleActivation of the mitogen-activated protein kinase pathway by the erythropoietin receptor
volume269
year1994
(literatureReference)[Complex:9029107] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1:Grb2-1:Sos1 [plasma membrane] [Mus musculus]
[CatalystActivityReference:9643836] protein tyrosine kinase activity of Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:Shc1 [plasma membrane] Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor
[Reaction:9027266] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1 binds Shc1 [Mus musculus]
[Pathway:9027284] Erythropoietin activates RAS [Homo sapiens]
[Reaction:9029146] Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1 binds Grb2-1:Sos1 [Mus musculus]
[Reaction:9029147] Jak2 phosphorylates Shc1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef:Shc1 [Mus musculus]
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