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Details on Person CPY4 ω-oxidises 14(S)-HDHA to MaR-L1

Class:Id	Reaction:9027042
_displayName	CPY4 ω-oxidises 14(S)-HDHA to MaR-L1
_doRelease	TRUE
_timestamp	2018-02-21 13:56:05
authored	[InstanceEdit:9027051] Jassal, Bijay, 2017-10-27
catalystActivity	[CatalystActivity:9020576] monooxygenase activity of CYP4 [endoplasmic reticulum membrane]
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:9027051] Jassal, Bijay, 2017-10-27
edited	[InstanceEdit:9027051] Jassal, Bijay, 2017-10-27
input	[SimpleEntity:9027029] 14(S)-HDHA [cytosol] [SimpleEntity:29364] NADPH [cytosol] [SimpleEntity:29368] O2 [cytosol] [SimpleEntity:70106] H+ [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9027018] Maresin-like lipid mediators are produced by leukocytes and platelets and rescue reparative function of diabetes-impaired macrophages
modified	[InstanceEdit:9027299] Jassal, Bijay, 2017-10-30 [InstanceEdit:9028878] Jassal, Bijay, 2017-11-13 [InstanceEdit:9029003] Jassal, Bijay, 2017-11-14 [InstanceEdit:9037605] Jassal, Bijay, 2018-02-20 [InstanceEdit:9037805] Jassal, Bijay, 2018-02-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CPY4 ω-oxidises 14(S)-HDHA to MaR-L1
output	[SimpleEntity:9027040] MaR-L1 [cytosol] [SimpleEntity:29356] H2O [cytosol] [SimpleEntity:29366] NADP+ [cytosol]
precedingEvent	[Reaction:9027033] Hydroperoxy reducatase reduces 14(S)-Hp-DHA to 14(S)-HDHA [Homo sapiens] [Reaction:9020274] ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9027059] R-HSA-9027042.2
summation	[Summation:9027312] Cytochrome P450 (CYP) enzymes are thought to ω-hydroxylate (...
(hasEvent)	[Pathway:9027307] Biosynthesis of maresin-like SPMs [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9031803] Maresin-like SPMs translocate from cytosol to extracellular region [Homo sapiens]
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No pathways have been reviewed or authored by CPY4 ω-oxidises 14(S)-HDHA to MaR-L1 (9027042)