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Details on Person IL7 binding enhances the association of Protein-tyrosine kin...
| Class:Id | Summation:9025942 |
|---|---|
| _displayName | IL7 binding enhances the association of Protein-tyrosine kin... |
| _timestamp | 2017-10-16 09:15:51 |
| created | [InstanceEdit:9025940] Jupe, Steve, 2017-10-16 |
| literatureReference | [LiteratureReference:8982793] Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha. |
| text | IL7 binding enhances the association of Protein-tyrosine kinase 2-beta (PTK2B, PYK2) physically associates with Tyrosine-protein kinase JAK1 (JAK1), increasing the association of JAK1 with IL7R (Benbernou et al. 2000). This is a black box event since PTK2B may bind indirectly to the IL7R:JAK1 complex via other cytosolic proteins. |
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No pathways have been reviewed or authored by IL7 binding enhances the association of Protein-tyrosine kin... (9025942)
