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Details on Person LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1

Class:Id	Reaction:9024890
_displayName	LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1
_doRelease	TRUE
_timestamp	2018-02-28 14:29:43
authored	[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
catalystActivity	[CatalystActivity:9022649] epoxide hydrolase activity of LTA4H:Zn2+ [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9024874] Jassal, Bijay, 2017-10-10
edited	[InstanceEdit:9020263] Jassal, Bijay, 2017-09-05
input	[SimpleEntity:9024873] 16S,17S-epoxy-DHA [cytosol] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9020250] Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes [LiteratureReference:9024475] Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation
modified	[InstanceEdit:9029500] Jassal, Bijay, 2017-11-20 [InstanceEdit:9037603] Jassal, Bijay, 2018-02-20 [InstanceEdit:9037792] Jassal, Bijay, 2018-02-21 [InstanceEdit:9037809] Jassal, Bijay, 2018-02-21 [InstanceEdit:9038501] Matthews, Lisa, 2018-02-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1
output	[SimpleEntity:9024886] (N)PD1 [cytosol]
precedingEvent	[Reaction:9024881] ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA [Homo sapiens] [Reaction:9020275] ALOX15 oxidises DHA to 17(S)-Hp-DHA [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9024902] R-HSA-9024890.2
summation	[Summation:9024894] Leukotriene A4 hydrolase (LTA4H) is a monomeric, soluble enz...
(hasEvent)	[Pathway:9018681] Biosynthesis of protectins [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9031807] Protectins translocate from cytosol to extracellular region [Homo sapiens] [Reaction:9037761] CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 [Homo sapiens]
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No pathways have been reviewed or authored by LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (9024890)