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Details on Person ALOX15 oxidises 17(S)-Hp-DHA to PDX

Class:Id	Reaction:9024872
_displayName	ALOX15 oxidises 17(S)-Hp-DHA to PDX
_doRelease	TRUE
_timestamp	2018-02-21 13:42:17
authored	[InstanceEdit:9024874] Jassal, Bijay, 2017-10-10
catalystActivity	[CatalystActivity:9022673] arachidonate 15-lipoxygenase activity of ALOX15 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9024874] Jassal, Bijay, 2017-10-10
edited	[InstanceEdit:9024874] Jassal, Bijay, 2017-10-10
input	[SimpleEntity:9024012] 17(S)-Hp-DHA [cytosol] [SimpleEntity:29368] O2 [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9020250] Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes [LiteratureReference:9024475] Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation [LiteratureReference:9024888] Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation
modified	[InstanceEdit:9028878] Jassal, Bijay, 2017-11-13 [InstanceEdit:9037603] Jassal, Bijay, 2018-02-20 [InstanceEdit:9037750] Jassal, Bijay, 2018-02-21 [InstanceEdit:9037802] Jassal, Bijay, 2018-02-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ALOX15 oxidises 17(S)-Hp-DHA to PDX
output	[SimpleEntity:9024883] PDX [cytosol]
precedingEvent	[Reaction:9020275] ALOX15 oxidises DHA to 17(S)-Hp-DHA [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9024903] R-HSA-9024872.2
summation	[Summation:9024878] 15-lipoxygenase (ALOX15) can mediate a second lipoxygenation...
(hasEvent)	[Pathway:9018681] Biosynthesis of protectins [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9031807] Protectins translocate from cytosol to extracellular region [Homo sapiens]
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No pathways have been reviewed or authored by ALOX15 oxidises 17(S)-Hp-DHA to PDX (9024872)