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Details on Person The liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice

Class:IdLiteratureReference:9024438
_displayNameThe liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice
_timestamp2017-10-03 21:27:51
author[Person:9024452] Verreault, Mélanie
[Person:9024459] Senekeo-Effenberger, Kathy
[Person:9024434] Trottier, Jocelyn
[Person:9024445] Bonzo, Jessica A
[Person:9024442] Bélanger, Julie
[Person:9024422] Kaeding, Jenny
[Person:4341044] Staels, Bart
[Person:9024435] Caron, Patrick
[Person:9024444] Tukey, Robert H
[Person:9024427] Barbier, Olivier
created[InstanceEdit:9024428] Shamovsky, Veronica, 2017-10-03
journalHepatology
pages368-78
pubMedIdentifier16871576
titleThe liver X-receptor alpha controls hepatic expression of the human bile acid-glucuronidating UGT1A3 enzyme in human cells and transgenic mice
volume44
year2006
(literatureReference)[Reaction:9029517] Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex [Homo sapiens]
[BlackBoxEvent:9029536] Expression of UGT1A3 [Homo sapiens]
[Reaction:9029566] Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene [Homo sapiens]
[Reaction:9029580] NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex [Homo sapiens]
[Pathway:9623433] NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis [Homo sapiens]
[Summation:9024421] The liver X receptors LXRα (NR1H3) and LXRβ (NR1H2) are memb...
[Summation:9029523] In transient transfection assays performed in human hepatoma...
[Summation:9029540] UDP Glucuronosyltransferase Family 1 Member A3 (UGT1A3) is a...
[Summation:9029549] In transient transfection assays performed in human hepatoma...
[Summation:9623896] Liver X receptors NR1H3 (LXR alpha) and NR1H2 (LXR beta) are...
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