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Details on Person Carboxypeptidase E (rat Carboxypeptidase H) cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87))

Class:IdReaction:9023186
_displayNameCarboxypeptidase E (rat Carboxypeptidase H) cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87))
_doReleaseTRUE
_timestamp2017-11-13 05:03:32
authored[InstanceEdit:9023203] May, Bruce, 2017-09-25
catalystActivity[CatalystActivity:9023160] metallocarboxypeptidase activity of Cpe:Zn2+ [secretory granule membrane]
catalystActivityReference[CatalystActivityReference:9643640] metallocarboxypeptidase activity of Cpe:Zn2+ [secretory granule membrane] The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processing
compartment[Compartment:216813] secretory granule membrane
created[InstanceEdit:9023176] May, Bruce, 2017-09-27
edited[InstanceEdit:9023203] May, Bruce, 2017-09-25
input[EntityWithAccessionedSequence:9023172] INS(57-89) [secretory granule lumen] [Homo sapiens]
isChimericTRUE
literatureReference[LiteratureReference:9023179] The insulin-secretory-granule carboxypeptidase H. Purification and demonstration of involvement in proinsulin processing
modified[InstanceEdit:9023615] May, Bruce, 2017-09-28
[InstanceEdit:9028862] Matthews, Lisa, 2017-11-13
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameCarboxypeptidase E (rat Carboxypeptidase H) cleaves C-peptide (Insulin(57-89)) to yield C-peptide (Insulin(57-87))
output[EntityWithAccessionedSequence:265011] C Peptide [secretory granule lumen] [Homo sapiens]
releaseDate2017-12-13
reviewed[InstanceEdit:387470] D'Eustachio, P, Matthews, L, Gillespie, ME, 2008-12-02 16:25:31
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
[Species:48895] Rattus norvegicus
stableIdentifier[StableIdentifier:9023215] R-NUL-9023186.3
summation[Summation:9023162] Carboxypeptidase E (also called Carboxypeptidase H) purified...
(inferredFrom)[Reaction:9023159] Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) [Homo sapiens]
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