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Details on Person MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
| Class:Id | LiteratureReference:9022452 |
| _displayName | MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system |
| _timestamp | 2017-09-22 20:05:54 |
| author | [Person:9022458] Mellén, Marian [Person:9022457] Ayata, Pinar [Person:9022454] Dewell, Scott [Person:9020952] Kriaucionis, Skirmantas [Person:5671898] Heintz, Nathaniel |
| created | [InstanceEdit:9022450] Orlic-Milacic, Marija, 2017-09-22 |
| journal | Cell |
| pages | 1417-30 |
| pubMedIdentifier | 23260135 |
| title | MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system |
| volume | 151 |
| year | 2012 |
| (literatureReference) | [Complex:9022463] MECP2:5mC-DNA [nucleoplasm] [Homo sapiens] [Complex:9022466] MECP2:5hmC-DNA [nucleoplasm] [Homo sapiens] [Pathway:8986944] Transcriptional Regulation by MECP2 [Homo sapiens] [Reaction:9022453] MECP2 binds 5hmC-DNA [Homo sapiens] [Reaction:9022456] MECP2 binds 5mC-DNA [Homo sapiens] [FailedReaction:9022462] MECP2 mutants R133C ,D121G, R133H and S134F do not bind 5hmC-DNA [Homo sapiens] [FailedReaction:9022465] MECP2 mutants R106W, D121G, R133H, S134F, T158M and T158A do not bind to 5mC-DNA [Homo sapiens] [Pathway:9022534] Loss of MECP2 binding ability to 5hmC-DNA [Homo sapiens] [Pathway:9022538] Loss of MECP2 binding ability to 5mC-DNA [Homo sapiens] |
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