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Details on Person Based on studies in rat, transcription of the GRIA2 (GLUR2) ...

Class:IdSummation:9022378
_displayNameBased on studies in rat, transcription of the GRIA2 (GLUR2) ...
_timestamp2018-04-05 20:25:29
created[InstanceEdit:9022376] Orlic-Milacic, Marija, 2017-09-22
literatureReference[LiteratureReference:9022360] The Rett syndrome protein MeCP2 regulates synaptic scaling
modified[InstanceEdit:9022443] Orlic-Milacic, Marija, 2017-09-22
[InstanceEdit:9024017] Orlic-Milacic, Marija, 2017-09-29
[InstanceEdit:9604959] Orlic-Milacic, Marija, 2018-04-05
textBased on studies in rat, transcription of the GRIA2 (GLUR2) gene, encoding glutamate receptor 2, is inhibited by binding of the MECP2:SIN3A:HDAC1 complex to the GRIA2 gene promoter. MECP2-mediated regulation of GRIA2 expression is involved in synaptic scaling (Qiu et al. 2012).
(summation)[BlackBoxEvent:9022365] GRIA2 gene expression is inhibited by MECP2:SIN3A complex [Homo sapiens]
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