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Details on Person HIPK2 phosphorylates MECP2

Class:IdReaction:9022314
_displayNameHIPK2 phosphorylates MECP2
_doReleaseTRUE
_timestamp2018-08-08 18:50:55
authored[InstanceEdit:9024208] Orlic-Milacic, Marija, 2017-10-02
catalystActivity[CatalystActivity:8878065] protein serine/threonine kinase activity of HIPK2 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9022306] Orlic-Milacic, Marija, 2017-09-22
edited[InstanceEdit:9615799] Orlic-Milacic, Marija, 2018-08-08
input[CandidateSet:9005549] MECP2 [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:9022311] Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis
[LiteratureReference:9006983] Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function
modified[InstanceEdit:9022338] Orlic-Milacic, Marija, 2017-09-22
[InstanceEdit:9608108] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9608115] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9608122] Orlic-Milacic, Marija, 2018-05-09
[InstanceEdit:9608281] Orlic-Milacic, Marija, 2018-05-11
[InstanceEdit:9615853] Orlic-Milacic, Marija, 2018-08-08
[InstanceEdit:9615854] Orlic-Milacic, Marija, 2018-08-08
[InstanceEdit:9615857] Orlic-Milacic, Marija, 2018-08-08
[InstanceEdit:9615861] Orlic-Milacic, Marija, 2018-08-08
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameHIPK2 phosphorylates MECP2
output[CandidateSet:9022332] p-S80-MECP2 [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
releaseDate2018-09-12
reviewed[InstanceEdit:9608119] Krishnaraj, Rahul, 2018-08-07
[InstanceEdit:9608114] Christodoulou, John, 2018-08-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9022325] R-HSA-9022314.2
summation[Summation:9022316] Nuclear serine/threonine protein kinase HIPK2 phosphorylates...
(hasEvent)[Pathway:9022692] Regulation of MECP2 expression and activity [Homo sapiens]
(precedingEvent)[Reaction:9022315] MECP2 binds DGCR8 [Homo sapiens]
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No pathways have been reviewed or authored by HIPK2 phosphorylates MECP2 (9022314)