Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-Actin:A-microtubule binds 2xKIF5B:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B and ATP

Class:IdBlackBoxEvent:9021126
_displayNameIL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-Actin:A-microtubule binds 2xKIF5B:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B and ATP
_doReleaseFALSE
_timestamp2017-10-20 10:20:15
compartment[Compartment:70101] cytosol
[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9021127] Duenas, Corina, 2017-09-14
input[SimpleEntity:113592] ATP [cytosol]
[Complex:9021756] IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-Actin:Microtubule [plasma membrane] [Homo sapiens]
[Complex:9021766] 2xKIF5B:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9021119] Microtubule-associated protein-like binding of the kinesin-1 tail to microtubules
modified[InstanceEdit:9021824] Duenas, Corina, 2017-09-21
[InstanceEdit:9021846] Duenas, Corina, 2017-09-21
[InstanceEdit:9022053] Duenas, Corina, 2017-09-21
[InstanceEdit:9022076] Duenas, Corina, 2017-09-21
[InstanceEdit:9022103] Duenas, Corina, 2017-09-21
[InstanceEdit:9022293] Duenas, Corina, 2017-09-22
[InstanceEdit:9026541] Jupe, Steve, 2017-10-20
nameIL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-Actin:A-microtubule binds 2xKIF5B:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B and ATP
p-STAT5/Kinesin-1 and ATP binds to microtubule after IL7/IL7R interacton
output[Complex:9021129] IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-actin:Microtubule:2x(KIF5B):ATP:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B [plasma membrane] [Homo sapiens]
precedingEvent
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9021130] R-HSA-9021126.1
summation[Summation:9021122] Kinesin‑1:cargo protein complex (the cargo protein is STAT5)...
(hasEvent)[Pathway:9024178] Intracellular Kinesin Motion
(precedingEvent)[BlackBoxEvent:9025941] STAT5 in IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-actin:A-microtubule:2x(KIF5B):ATP:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B is phosphorylated [Homo sapiens]
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No pathways have been reviewed or authored by IL7:p-Y449-IL7R:JAK1:p-FYN:IL2RG:p-JAK3:MSN,EZR:F-Actin:A-microtubule binds 2xKIF5B:2x(KLC1,KLC2,KLC3,KLC4):STAT5A,STAT5B and ATP (9021126)