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Details on Person LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2

Class:Id	Reaction:9020252
_displayName	LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2
_doRelease	TRUE
_timestamp	2018-02-21 14:13:00
authored	[InstanceEdit:9020263] Jassal, Bijay, 2017-09-05
catalystActivity	[CatalystActivity:9022649] epoxide hydrolase activity of LTA4H:Zn2+ [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9020263] Jassal, Bijay, 2017-09-05
edited	[InstanceEdit:9020263] Jassal, Bijay, 2017-09-05
input	[SimpleEntity:9024602] 7S(8)-epoxy-17(R)-HDHA [cytosol] [SimpleEntity:29356] H2O [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9024464] Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation [LiteratureReference:9024597] Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis [LiteratureReference:9022657] Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
modified	[InstanceEdit:9020459] Jassal, Bijay, 2017-09-06 [InstanceEdit:9024471] Jassal, Bijay, 2017-10-04 [InstanceEdit:9024583] Jassal, Bijay, 2017-10-06 [InstanceEdit:9024788] Jassal, Bijay, 2017-10-09 [InstanceEdit:9037602] Jassal, Bijay, 2018-02-20 [InstanceEdit:9037809] Jassal, Bijay, 2018-02-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2
output	[DefinedSet:9024574] AT-RvD1, AT-RvD2 [cytosol]
precedingEvent	[Reaction:9020256] ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA [Homo sapiens] [Reaction:9020251] ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9020286] R-HSA-9020252.2
summation	[Summation:9024594] Leukotriene A4 hydrolase (LTA4H) is a monomeric, soluble enz...
(hasEvent)	[Pathway:9020265] Biosynthesis of aspirin-triggered D-series resolvins [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9024586] AT-RvD1-6 translocate from cytosol to extracellular region [Homo sapiens]
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No pathways have been reviewed or authored by LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (9020252)