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Details on Person ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3

Class:Id	Reaction:9018907
_displayName	ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3
_doRelease	TRUE
_timestamp	2018-02-21 13:42:23
authored	[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
catalystActivity	[CatalystActivity:9022673] arachidonate 15-lipoxygenase activity of ALOX15 [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
edited	[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
input	[SimpleEntity:9023651] 18(R)-HEPE [cytosol] [SimpleEntity:29368] O2 [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9018890] Identification and structure determination of novel anti-inflammatory mediator resolvin E3, 17,18-dihydroxyeicosapentaenoic acid [LiteratureReference:9023647] Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3
modified	[InstanceEdit:9022652] Jassal, Bijay, 2017-09-25 [InstanceEdit:9023654] Jassal, Bijay, 2017-09-28 [InstanceEdit:9023707] Jassal, Bijay, 2017-09-28 [InstanceEdit:9037599] Jassal, Bijay, 2018-02-20 [InstanceEdit:9037802] Jassal, Bijay, 2018-02-21 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3
output	[SimpleEntity:9023644] (18R)-resolvin E3 [cytosol]
precedingEvent	[Reaction:9018895] GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE [Homo sapiens] [Reaction:9018880] Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE [Homo sapiens]
releaseDate	2018-03-21
reviewed	[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9018944] R-HSA-9018907.2
summation	[Summation:9018884] Unlike resolvins E1 and E2, both of which are biosynthesised...
(hasEvent)	[Pathway:9023661] Biosynthesis of E-series 18(R)-resolvins [Homo sapiens]
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No pathways have been reviewed or authored by ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (9018907)