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Details on Person ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE

Class:IdReaction:9018859
_displayNameALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE
_doReleaseTRUE
_timestamp2018-02-21 13:47:13
authored[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
catalystActivity[CatalystActivity:9020578] oxidoreductase activity, acting on single donors with incorporation of molecular oxygen of ALOX5 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
edited[InstanceEdit:9018893] Jassal, Bijay, 2017-09-05
input[SimpleEntity:9020602] 5(S)-Hp-18(S)-HEPE [cytosol]
[SimpleEntity:29368] O2 [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9020605] Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis
[LiteratureReference:9023641] Resolvin E2 formation and impact in inflammation resolution
modified[InstanceEdit:9022652] Jassal, Bijay, 2017-09-25
[InstanceEdit:9023654] Jassal, Bijay, 2017-09-28
[InstanceEdit:9023707] Jassal, Bijay, 2017-09-28
[InstanceEdit:9037598] Jassal, Bijay, 2018-02-20
[InstanceEdit:9037792] Jassal, Bijay, 2018-02-21
[InstanceEdit:9037803] Jassal, Bijay, 2018-02-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE
output[SimpleEntity:9022655] 5S,6S-epoxy-18(S)-HEPE [cytosol]
precedingEvent
releaseDate2018-03-21
reviewed[InstanceEdit:9037799] Hansen, Trond Vidar, 2018-02-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9018932] R-HSA-9018859.2
summation[Summation:9022680] In neutrophils, 5-lipoxygenase (ALOX5) can mediate the inser...
(hasEvent)[Pathway:9018896] Biosynthesis of E-series 18(S)-resolvins [Homo sapiens]
(precedingEvent)[Reaction:9018862] LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 [Homo sapiens]
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No pathways have been reviewed or authored by ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE (9018859)