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Details on Person RHOT2 binds effectors at the mitochondrial outer membrane

Class:Id	Reaction:9018824
_displayName	RHOT2 binds effectors at the mitochondrial outer membrane
_doRelease	TRUE
_timestamp	2021-02-25 16:34:10
authored	[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
compartment	[Compartment:70101] cytosol [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:9018828] Orlic-Milacic, Marija, 2017-09-05
edited	[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
input	[Complex:9020438] RHOT2:GTP [mitochondrial outer membrane] [Homo sapiens] [DefinedSet:9020433] RHOT2 effectors [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9693816] The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking [LiteratureReference:9693834] MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca²⁺ Stress [LiteratureReference:9693847] Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX [LiteratureReference:9693859] The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes
modified	[InstanceEdit:9018833] Orlic-Milacic, Marija, 2017-09-05 [InstanceEdit:9020457] Orlic-Milacic, Marija, 2017-09-05 [InstanceEdit:9693753] Orlic-Milacic, Marija, 2020-07-06 [InstanceEdit:9693819] Orlic-Milacic, Marija, 2020-07-07 [InstanceEdit:9693841] Orlic-Milacic, Marija, 2020-07-07 [InstanceEdit:9693854] Orlic-Milacic, Marija, 2020-07-07 [InstanceEdit:9693864] Orlic-Milacic, Marija, 2020-07-07 [InstanceEdit:9694018] Orlic-Milacic, Marija, 2020-07-08 [InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24 [InstanceEdit:9714637] Orlic-Milacic, Marija, 2021-02-12 [InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17 [InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RHOT2 binds effectors at the mitochondrial outer membrane
output	[Complex:9020439] RHOT2:GTP:RHOT2 effectors [mitochondrial outer membrane] [Homo sapiens]
precedingEvent	[Reaction:9018825] RHOT2 GEFs activate RHOT2 [Homo sapiens]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9714635] Schrader, Michael, 2021-02-09 [InstanceEdit:9714634] Castro, In�s G, 2021-02-09
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9018832] R-HSA-9018824.2
summation	[Summation:9693810] Active GTP-bound RHOT2 interacts with the following effector...
(hasEvent)	[Pathway:9013419] RHOT2 GTPase cycle [Homo sapiens]
(replacementInstances)	[_Deleted:9716816] Deletion of instance: 194894
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No pathways have been reviewed or authored by RHOT2 binds effectors at the mitochondrial outer membrane (9018824)