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Details on Person RHOBTB2 binds interacting proteins at the endosome membrane

Class:Id	Reaction:9018787
_displayName	RHOBTB2 binds interacting proteins at the endosome membrane
_doRelease	TRUE
_timestamp	2021-02-19 19:36:37
authored	[InstanceEdit:9677558] Orlic-Milacic, Marija, 2020-03-06
compartment	[Compartment:74700] endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:9018784] Orlic-Milacic, Marija, 2017-09-05
edited	[InstanceEdit:9706879] Orlic-Milacic, Marija, 2020-11-09
input	[Complex:9020344] RHOBTB2:GTP [endosome membrane] [Homo sapiens] [CandidateSet:9020341] RHOBTB2 interacting proteins [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9693647] Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex [LiteratureReference:9693699] Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism [LiteratureReference:9693702] RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex [LiteratureReference:9706007] DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancer [LiteratureReference:9679344] Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms
modified	[InstanceEdit:9020357] Orlic-Milacic, Marija, 2017-09-05 [InstanceEdit:9693704] Orlic-Milacic, Marija, 2020-07-06 [InstanceEdit:9694018] Orlic-Milacic, Marija, 2020-07-08 [InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24 [InstanceEdit:9706004] Orlic-Milacic, Marija, 2020-11-04 [InstanceEdit:9706013] Orlic-Milacic, Marija, 2020-11-04 [InstanceEdit:9706567] Orlic-Milacic, Marija, 2020-11-06 [InstanceEdit:9706879] Orlic-Milacic, Marija, 2020-11-09 [InstanceEdit:9706880] Orlic-Milacic, Marija, 2020-11-09 [InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715160] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17 [InstanceEdit:9716171] Orlic-Milacic, Marija, 2021-02-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RHOBTB2 binds interacting proteins at the endosome membrane
output	[Complex:9020346] RHOBTB2:GTP:RHOBTB2 interacting proteins [endosome membrane] [Homo sapiens]
precedingEvent	[Reaction:9018785] RHOBTB2 binds GTP [Homo sapiens]
releaseDate	2020-12-08
reviewed	[InstanceEdit:9705970] Rivero Crespo, Francisco, 2020-10-13 [InstanceEdit:9714226] Fort, Philippe, 2021-02-05
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:9714783] Orlic-Milacic, Marija, 2021-02-14
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9018792] R-HSA-9018787.3
summation	[Summation:9693701] RHOBTB2, like the other RHOBTB family member, RHOBTB1, and t...
(hasEvent)	[Pathway:9013418] RHOBTB2 GTPase cycle [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9776350] Update Tracker - [Reaction:9018787] RHOBTB2 binds interacting proteins at the endosome membrane - v76:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by RHOBTB2 binds interacting proteins at the endosome membrane (9018787)