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Details on Person RHOU auto-activates
Class:Id Reaction:9018768
_displayName RHOU auto-activates
_doRelease TRUE
_timestamp 2021-04-15 13:46:08
authored [InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
catalystActivity [CatalystActivity:9693872] guanyl-nucleotide exchange factor activity of RHOU:GDP [plasma membrane]
compartment [Compartment:876] plasma membrane [Compartment:70101] cytosol
created [InstanceEdit:9018764] Orlic-Milacic, Marija, 2017-09-05
edited [InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25 [InstanceEdit:9727277] Orlic-Milacic, Marija, 2021-04-15
input [SimpleEntity:29438] GTP [cytosol] [Complex:9019557] RHOU:GDP [plasma membrane] [Homo sapiens]
isChimeric FALSE
literatureReference [LiteratureReference:9035998] Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase [LiteratureReference:9693867] Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects
modified [InstanceEdit:9019621] Orlic-Milacic, Marija, 2017-09-05 [InstanceEdit:9693874] Orlic-Milacic, Marija, 2020-07-07 [InstanceEdit:9695527] Orlic-Milacic, Marija, 2020-07-14 [InstanceEdit:9695623] Orlic-Milacic, Marija, 2020-07-15 [InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24 [InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715161] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17 [InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25 [InstanceEdit:9726810] Orlic-Milacic, Marija, 2021-04-12 [InstanceEdit:9727278] Orlic-Milacic, Marija, 2021-04-15 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name RHOU auto-activates
output [Complex:9019560] RHOU:GTP [plasma membrane] [Homo sapiens] [SimpleEntity:29420] GDP [cytosol]
releaseDate 2021-03-23
reviewed [InstanceEdit:9714226] Fort, Philippe, 2021-02-05 [InstanceEdit:9726808] Shepelev, Mikhail V, 2021-03-30
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9018772] R-HSA-9018768.3
summation [Summation:9693869] RHOU is an atypical RHO GTPase with a high intrinsic guanine...
(hasEvent) [Pathway:9013420] RHOU GTPase cycle [Homo sapiens]
(precedingEvent) [Reaction:9018766] RHOU binds effectors at the plasma membrane [Homo sapiens]
(updatedInstance) [_UpdateTracker:9776203] Update Tracker - [Reaction:9018768] RHOU auto-activates - v77:[modifyText]
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