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Details on Person RHOU auto-activates

Class:IdReaction:9018768
_displayNameRHOU auto-activates
_doReleaseTRUE
_timestamp2021-04-15 13:46:08
authored[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
catalystActivity[CatalystActivity:9693872] guanyl-nucleotide exchange factor activity of RHOU:GDP [plasma membrane]
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:9018764] Orlic-Milacic, Marija, 2017-09-05
edited[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
[InstanceEdit:9727277] Orlic-Milacic, Marija, 2021-04-15
input[SimpleEntity:29438] GTP [cytosol]
[Complex:9019557] RHOU:GDP [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9035998] Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase
[LiteratureReference:9693867] Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects
modified[InstanceEdit:9019621] Orlic-Milacic, Marija, 2017-09-05
[InstanceEdit:9693874] Orlic-Milacic, Marija, 2020-07-07
[InstanceEdit:9695527] Orlic-Milacic, Marija, 2020-07-14
[InstanceEdit:9695623] Orlic-Milacic, Marija, 2020-07-15
[InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18
[InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24
[InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16
[InstanceEdit:9715161] Orlic-Milacic, Marija, 2021-02-16
[InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17
[InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23
[InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25
[InstanceEdit:9726810] Orlic-Milacic, Marija, 2021-04-12
[InstanceEdit:9727278] Orlic-Milacic, Marija, 2021-04-15
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameRHOU auto-activates
output[Complex:9019560] RHOU:GTP [plasma membrane] [Homo sapiens]
[SimpleEntity:29420] GDP [cytosol]
releaseDate2021-03-23
reviewed[InstanceEdit:9714226] Fort, Philippe, 2021-02-05
[InstanceEdit:9726808] Shepelev, Mikhail V, 2021-03-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9018772] R-HSA-9018768.3
summation[Summation:9693869] RHOU is an atypical RHO GTPase with a high intrinsic guanine...
(hasEvent)[Pathway:9013420] RHOU GTPase cycle [Homo sapiens]
(precedingEvent)[Reaction:9018766] RHOU binds effectors at the plasma membrane [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776203] Update Tracker - [Reaction:9018768] RHOU auto-activates - v77:[modifyText]
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No pathways have been reviewed or authored by RHOU auto-activates (9018768)