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Details on Person Binding of NOTCH3 to YBX1 (YB-1) triggers cleavage of NOTCH3...
| Class:Id | Summation:9017818 |
|---|---|
| _displayName | Binding of NOTCH3 to YBX1 (YB-1) triggers cleavage of NOTCH3... |
| _timestamp | 2017-09-18 19:31:47 |
| created | [InstanceEdit:9017816] Orlic-Milacic, Marija, 2017-08-25 |
| modified | [InstanceEdit:9021510] Orlic-Milacic, Marija, 2017-09-18 |
| text | Binding of NOTCH3 to YBX1 (YB-1) triggers cleavage of NOTCH3 by the gamma-secretase complex. The exact steps of YBX1-mediated NOTCH3 activation are not known. The gamma-secretase complex releases NOTCH3 intracellular domain (NICD3), leading to activation of NOTCH3 target genes downstream of YBX1 (Rauen et al. 2009). |
| (summation) | [BlackBoxEvent:9017817] Gamma-secretase cleaves YBX1:NOTCH3 [Homo sapiens] |
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No pathways have been reviewed or authored by Binding of NOTCH3 to YBX1 (YB-1) triggers cleavage of NOTCH3... (9017818)
