Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person FN1 binds COL5A1-defective collagen types I-V, VII

Class:Id	Reaction:9017758
_displayName	FN1 binds COL5A1-defective collagen types I-V, VII
_timestamp	2017-08-25 10:43:16
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9017752] Varusai, Thawfeek, 2017-08-25
disease	[Disease:3656228] Ehlers-Danlos syndrome
input	[EntityWithAccessionedSequence:54851] FN1(32-2477) [extracellular region] [Homo sapiens] [DefinedSet:9017756] Collagen types I-V, VII with defective COL5A1 [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2327742] Interaction of fibronectin with C1q and collagen. Effects of ionic strength and denaturation of the collagenous component [LiteratureReference:9014027] Comprehensive molecular analysis demonstrates type V collagen mutations in over 90% of patients with classic EDS and allows to refine diagnostic criteria [LiteratureReference:9014031] Order of intron removal influences multiple splice outcomes, including a two-exon skip, in a COL5A1 acceptor-site mutation that results in abnormal pro-alpha1(V) N-propeptides and Ehlers-Danlos syndrome type I
modified	[InstanceEdit:9017772] Varusai, Thawfeek, 2017-08-25
name	FN1 binds COL5A1-defective collagen types I-V, VII Fibronectin binds COL5A1-defective collagen types I-IV, VII
normalReaction	[Reaction:2327733] FN1 binds Collagen types I-V, VII [Homo sapiens]
output	[Complex:9017761] FN1(32-2386):Collagen types I-V, VII with defective COL5A1 [extracellular region] [Homo sapiens]
precedingEvent	[Polymerisation:9014269] Formation of defective COL5A1 collagen fibrils [Homo sapiens] [Reaction:9014217] Removal of defective COL5A1 fibrillar collagen N - propeptides [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9017771] R-HSA-9017758.1
summation	[Summation:9017762] Fibronectin (FN1) binds many types of collagen, particularly...
(hasEvent)	[Pathway:9945338] Disorders of fibronectin-collagen interaction [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by FN1 binds COL5A1-defective collagen types I-V, VII (9017758)