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Details on Person Fibronectin (FN1) binds many types of collagen, particularly...
| Class:Id | Summation:9017755 |
|---|---|
| _displayName | Fibronectin (FN1) binds many types of collagen, particularly... |
| _timestamp | 2017-09-06 10:05:29 |
| created | [InstanceEdit:9017752] Varusai, Thawfeek, 2017-08-25 |
| modified | [InstanceEdit:9017772] Varusai, Thawfeek, 2017-08-25 [InstanceEdit:9020462] Varusai, Thawfeek, 2017-09-06 |
| text | Fibronectin (FN1) binds many types of collagen, particularly when denatured. Collagen alpha-1(VII) chain (COL7A1) is a procollagen peptide that is primarily involved in the formation of anchoring fibrils. Mutations in COL7A1 may result in defective synthesis, processing and functioning of anchoring fibrils, which leads to disorders such as dystrophic epidermolysis bullosa Glycine residue substitutions are the most common type of mutations. COL7A1 mutations may result in abnormal protein conformations or altered type VII collagen that may interfere with its function (Jarvikallio A et al. 1997, Dang N et al. 2008). |
| (summation) | [Reaction:9017760] FN1 binds COL7A1-defective collagen types I-V, VII [Homo sapiens] |
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No pathways have been reviewed or authored by Fibronectin (FN1) binds many types of collagen, particularly... (9017755)
