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Details on Person FN1 binds COL1A1-defective collagen types I-V, VII

Class:Id	Reaction:9017751
_displayName	FN1 binds COL1A1-defective collagen types I-V, VII
_timestamp	2017-08-25 10:43:11
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9017752] Varusai, Thawfeek, 2017-08-25
disease	[Disease:9015256] osteogenesis imperfecta
input	[EntityWithAccessionedSequence:54851] FN1(32-2477) [extracellular region] [Homo sapiens] [DefinedSet:9017757] Collagen types I-V, VII with defective COL1A1 [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2327742] Interaction of fibronectin with C1q and collagen. Effects of ionic strength and denaturation of the collagenous component [LiteratureReference:9015250] The human type I collagen mutation database [LiteratureReference:9015589] Mutations in type I collagen genes resulting in osteogenesis imperfecta in humans
modified	[InstanceEdit:9017772] Varusai, Thawfeek, 2017-08-25
name	FN1 binds COL1A1-defective collagen types I-V, VII Fibronectin binds COL1A1-defective collagen types I-IV, VII
normalReaction	[Reaction:2327733] FN1 binds Collagen types I-V, VII [Homo sapiens]
output	[Complex:9017753] FN1(32-2386):Collagen types I-V, VII with defective COL1A1 [extracellular region] [Homo sapiens]
precedingEvent	[Polymerisation:9015584] Formation of defective COL1A1 collagen fibrils [Homo sapiens] [Reaction:2002440] Removal of fibrillar collagen C-propeptides [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9017763] R-HSA-9017751.1
summation	[Summation:9017750] Fibronectin (FN1) binds many types of collagen, particularly...
(hasEvent)	[Pathway:9945338] Disorders of fibronectin-collagen interaction [Homo sapiens]
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No pathways have been reviewed or authored by FN1 binds COL1A1-defective collagen types I-V, VII (9017751)