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Details on Person Defective collagen type VII fibril [extracellular region]

Class:Id	Polymer:9017288
_displayName	Defective collagen type VII fibril [extracellular region]
_timestamp	2017-08-17 15:35:51
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9017290] Varusai, Thawfeek, 2017-08-17
disease	[Disease:9016965] epidermolysis bullosa dystrophica
modified	[InstanceEdit:9017331] Varusai, Thawfeek, 2017-08-17
name	Defective collagen type VII fibril
repeatedUnit	[Complex:9017281] Abnormal collagen type VII -NC2 hexamer [extracellular region] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9017321] R-HSA-9017288.1
(hasComponent)	[Complex:9017304] Defective anchoring fibril complex [extracellular region] [Homo sapiens] [Complex:9017779] Defective collagen type VII fibril:Laminin-332 [extracellular region] [Homo sapiens] [Complex:9018039] Collagen type IV networks:Defective collagen type VII fibril [extracellular region] [Homo sapiens] [Complex:9018711] COL7A1-defective collagen type VII fibril:Integrin alpha2beta1 [plasma membrane] [Homo sapiens]
(hasMember)	[DefinedSet:9017754] Collagen types I-V, VII with defective COL7A1 [extracellular region] [Homo sapiens]
(input)	[Reaction:9017296] Abnormal collagen type VII binds laminin-322 and collagen IV [Homo sapiens] [Reaction:9017776] Laminin-332 binds abnormal collagen type VII [Homo sapiens] [Reaction:9018041] Defective collagen type VII binds collagen type IV [Homo sapiens] [Reaction:9018369] COL7A1-defective collagen type VII degradation by MMP1,2,3 [Homo sapiens] [Reaction:9018708] COL7A1-defective collagen type VII binds integrin alpha2beta1 [Homo sapiens]
(output)	[Polymerisation:9017286] Formation of abnormal anchoring fibrils [Homo sapiens]
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No pathways have been reviewed or authored by Defective collagen type VII fibril [extracellular region] (9017288)