Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person PTCRA gene expression is stimulated by NOTCH3 and inhibited by IK1

Class:Id	BlackBoxEvent:9016861
_displayName	PTCRA gene expression is stimulated by NOTCH3 and inhibited by IK1
_doRelease	TRUE
_timestamp	2017-11-02 15:38:10
authored	[InstanceEdit:9021699] Orlic-Milacic, Marija, 2017-09-20
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9016862] Orlic-Milacic, Marija, 2017-08-16
edited	[InstanceEdit:9027527] Orlic-Milacic, Marija, 2017-11-02
goBiologicalProcess	[GO_BiologicalProcess:20142] positive regulation of transcription of Notch receptor target
inferredFrom	[BlackBoxEvent:9016859] Ptcra gene expression is positively stimulated by Notch3 and inhibited by Ik1 [Mus musculus]
input	[EntityWithAccessionedSequence:9016877] PTCRA gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:9016882] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9016907] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9016922] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9017133] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9024182] Orlic-Milacic, Marija, 2017-10-02 [InstanceEdit:9027523] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9027526] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9027528] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9027530] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PTCRA gene expression is stimulated by NOTCH3 and inhibited by IK1
output	[EntityWithAccessionedSequence:9016879] PTCRA [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9016916] NOTCH3 coactivator complex binds the PTCRA gene promoter [Homo sapiens] [Reaction:9013631] NICD3 binds RBPJ and MAML in the nucleus [Homo sapiens] [BlackBoxEvent:9017120] IK1 binds the PTCRA gene promoter [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9016899] Positive gene expression regulation by 'NOTCH3 coactivator complex:PTCRA gene [nucleoplasm]' [NegativeGeneExpressionRegulation:9017136] Negative gene expression regulation by 'IK1:PTCRA gene [nucleoplasm]'
releaseDate	2017-12-13
reviewed	[InstanceEdit:9027525] Haw, Robin, 2017-10-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9016863] R-HSA-9016861.3
summation	[Summation:9016905] Based on studies in mice, NOTCH3 intracellular domain NICD3 ...
(hasEvent)	[Pathway:9013508] NOTCH3 Intracellular Domain Regulates Transcription [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by PTCRA gene expression is stimulated by NOTCH3 and inhibited by IK1 (9016861)