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Details on Person Ptcra gene expression is positively stimulated by Notch3 and inhibited by Ik1

Class:Id	BlackBoxEvent:9016859
_displayName	Ptcra gene expression is positively stimulated by Notch3 and inhibited by Ik1
_doRelease	TRUE
_timestamp	2017-11-02 15:24:30
authored	[InstanceEdit:9021699] Orlic-Milacic, Marija, 2017-09-20
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:9016862] Orlic-Milacic, Marija, 2017-08-16
edited	[InstanceEdit:9027527] Orlic-Milacic, Marija, 2017-11-02
input	[EntityWithAccessionedSequence:9016890] Ptcra gene [nucleoplasm] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:9015723] Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma [LiteratureReference:9016860] Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing
modified	[InstanceEdit:9016882] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9016894] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9016907] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9017133] Orlic-Milacic, Marija, 2017-08-16 [InstanceEdit:9027523] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9027527] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9027528] Orlic-Milacic, Marija, 2017-11-02 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ptcra gene expression is positively stimulated by Notch3 and inhibited by Ik1
output	[EntityWithAccessionedSequence:9016887] Ptcra [plasma membrane] [Mus musculus]
regulatedBy	[PositiveRegulation:9016898] Positive regulation by 'Notch3 coactivator complex [nucleoplasm]' [NegativeGeneExpressionRegulation:9017135] Negative gene expression regulation by 'Ik1:Ptcra gene [nucleoplasm]'
regulationReference	[RegulationReference:9641389] Negative gene expression regulation by 'Ik1:Ptcra gene [nucleoplasm]' Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing [RegulationReference:9642464] Positive regulation by 'Notch3 coactivator complex [nucleoplasm]' Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma
releaseDate	2017-12-13
reviewed	[InstanceEdit:9027525] Haw, Robin, 2017-10-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9016864] R-MMU-9016859.4
summation	[Summation:9016904] Mouse Notch3 intracellular domain, NICD3, induces transcript...
(inferredFrom)	[BlackBoxEvent:9016861] PTCRA gene expression is stimulated by NOTCH3 and inhibited by IK1 [Homo sapiens]
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