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Details on Person RUNX2-P2 binds RUNX2 gene promoter

Class:Id	Reaction:9016526
_displayName	RUNX2-P2 binds RUNX2 gene promoter
_doRelease	TRUE
_timestamp	2017-08-14 17:59:22
authored	[InstanceEdit:9016528] Orlic-Milacic, Marija, 2017-08-14
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9016528] Orlic-Milacic, Marija, 2017-08-14
edited	[InstanceEdit:9016528] Orlic-Milacic, Marija, 2017-08-14
inferredFrom	[Reaction:9016554] Runx2-P2 binds to Runx2 gene promoter [Mus musculus]
input	[Complex:9016525] RUNX2-P2:CBFB [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8939903] RUNX2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9016476] A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development
modified	[InstanceEdit:9016551] Orlic-Milacic, Marija, 2017-08-14 [InstanceEdit:9016560] Orlic-Milacic, Marija, 2017-08-14 [InstanceEdit:9016599] Orlic-Milacic, Marija, 2017-08-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX2-P2 binds RUNX2 gene promoter
output	[Complex:9016527] RUNX2-P2:CBFB:RUNX2 gene [nucleoplasm] [Homo sapiens]
releaseDate	2017-09-12
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9016533] R-HSA-9016526.2
summation	[Summation:9016550] Based on studies in mice, RUNX2-P2 (RUNX2 variant expressed ...
(hasEvent)	[Pathway:8939902] Regulation of RUNX2 expression and activity [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8939900] RUNX2 gene expression from proximal (P2) promoter is stimulated by ESR1:estrogen, ESRRA:PPARG1CA, TWIST1 and RUNX2-P2, and inhibited by ESRRA:PPARG1CB and DEXA:NR3C1 [Homo sapiens]
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No pathways have been reviewed or authored by RUNX2-P2 binds RUNX2 gene promoter (9016526)