Query author contributions in Reactome
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Details on Person miRNA-23b targets and inhibits TGF-beta-activated kinase 1 a...
| Class:Id | Summation:9015681 |
|---|---|
| _displayName | miRNA-23b targets and inhibits TGF-beta-activated kinase 1 a... |
| _timestamp | 2017-08-10 23:38:38 |
| created | [InstanceEdit:9015682] Duenas, Corina, 2017-08-10 |
| literatureReference | [LiteratureReference:8980116] The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α |
| text | miRNA-23b targets and inhibits TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (TAB2), TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (TAB3) and Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK or IKKalpha). Interleukin-17 (IL17) regulates miR-23b expression at the transcriptional level and possibility post-transcriptionally. Moreover miR-23b overexpression down-regulates TAB2, TAB3 and IKK-alpha (Zhu et al.2012). This is a black box event because the steps of transcription of miR-23b are ommited. |
| (summation) | [BlackBoxEvent:9015004] NFKB1(1-433):RELA binds to miR23a gene [Homo sapiens] |
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No pathways have been reviewed or authored by miRNA-23b targets and inhibits TGF-beta-activated kinase 1 a... (9015681)
