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Details on Person Factor Xa inhibitors bind Va:Xa

Class:IdReaction:9015122
_displayNameFactor Xa inhibitors bind Va:Xa
_doReleaseTRUE
_timestamp2020-07-23 13:59:45
authored[InstanceEdit:9015121] Jassal, Bijay, 2017-08-08
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9015121] Jassal, Bijay, 2017-08-08
edited[InstanceEdit:9015121] Jassal, Bijay, 2017-08-08
input[Complex:140662] FVa:FXa [plasma membrane] [Homo sapiens]
[DefinedSet:9038743] Factor Xa inhibitors [extracellular region]
isChimericFALSE
literatureReference[LiteratureReference:9015065] Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor
[LiteratureReference:9038770] Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
[LiteratureReference:9038767] The new factor Xa inhibitor: Apixaban
[LiteratureReference:9038773] Edoxaban, a Novel Oral Factor Xa Inhibitor
[LiteratureReference:9603677] Efficacy and toxicity of factor Xa inhibitors
modified[InstanceEdit:9015124] Jassal, Bijay, 2017-08-08
[InstanceEdit:9015125] Jassal, Bijay, 2017-08-08
[InstanceEdit:9015131] Jassal, Bijay, 2017-08-08
[InstanceEdit:9017374] Jassal, Bijay, 2017-08-21
[InstanceEdit:9038793] Jassal, Bijay, 2018-03-14
[InstanceEdit:9603675] Jassal, Bijay, 2018-03-23
[InstanceEdit:9605575] Jassal, Bijay, 2018-04-16
[InstanceEdit:9696624] Jassal, Bijay, 2020-07-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameFactor Xa inhibitors bind Va:Xa
output[Complex:9015116] Va:Xa:Factor Xa inhibitors [plasma membrane] [Homo sapiens]
releaseDate2018-06-12
reviewed[InstanceEdit:9605574] Gómez-Outes, Antonio, 2018-04-16
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9015123] R-HSA-9015122.3
summation[Summation:9015120] Factor Xa (aka Factor X heavy chain), a cleavage product of ...
(hasEvent)[Pathway:140875] OBSOLETE_Common Pathway of Fibrin Clot Formation_REPLACEMENT_9769743_9769733 [Homo sapiens]
[Pathway:9769739] Regulation of clotting cascade [Homo sapiens]
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No pathways have been reviewed or authored by Factor Xa inhibitors bind Va:Xa (9015122)