Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person RHOG GEFs activate RHOG

Class:Id	Reaction:9014433
_displayName	RHOG GEFs activate RHOG
_doRelease	TRUE
_timestamp	2021-02-25 16:33:21
authored	[InstanceEdit:9695572] Orlic-Milacic, Marija, 2020-07-14
catalystActivity	[CatalystActivity:9014439] guanyl-nucleotide exchange factor activity of RHOG GEFs [cytosol]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9014435] Orlic-Milacic, Marija, 2017-07-28
edited	[InstanceEdit:9716798] Orlic-Milacic, Marija, 2021-02-25
input	[Complex:9014438] RHOG:GDP [plasma membrane] [Homo sapiens] [SimpleEntity:29438] GTP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:9644217] Deciphering the molecular and functional basis of Dbl family proteins: a novel systematic approach toward classification of selective activation of the Rho family proteins [LiteratureReference:9692967] Kalirin Dbl-homology guanine nucleotide exchange factor 1 domain initiates new axon outgrowths via RhoG-mediated mechanisms [LiteratureReference:9644429] Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins [LiteratureReference:9692946] P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils [LiteratureReference:5229003] Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2 [LiteratureReference:9679395] Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism [LiteratureReference:9692965] Ephexin4 and EphA2 mediate resistance to anoikis through RhoG and phosphatidylinositol 3-kinase [LiteratureReference:9679397] SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis [LiteratureReference:8980837] Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5 [LiteratureReference:9692903] RhoG signals in parallel with Rac1 and Cdc42 [LiteratureReference:9692974] The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth [LiteratureReference:9644570] Characterization of the activation of small GTPases by their GEFs on membranes using artificial membrane tethering [LiteratureReference:9692966] Guanine nucleotide exchange catalyzed by dbl oncogene product [LiteratureReference:9714742] TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG
modified	[InstanceEdit:9692970] Orlic-Milacic, Marija, 2020-06-27 [InstanceEdit:9692979] Orlic-Milacic, Marija, 2020-06-27 [InstanceEdit:9693036] Orlic-Milacic, Marija, 2020-06-29 [InstanceEdit:9697611] Orlic-Milacic, Marija, 2020-08-18 [InstanceEdit:9698215] Orlic-Milacic, Marija, 2020-08-24 [InstanceEdit:9714743] Orlic-Milacic, Marija, 2021-02-14 [InstanceEdit:9714838] Orlic-Milacic, Marija, 2021-02-15 [InstanceEdit:9715101] Orlic-Milacic, Marija, 2021-02-16 [InstanceEdit:9715390] Orlic-Milacic, Marija, 2021-02-17 [InstanceEdit:9716668] Orlic-Milacic, Marija, 2021-02-23 [InstanceEdit:9716785] Orlic-Milacic, Marija, 2021-02-24 [InstanceEdit:9716799] Orlic-Milacic, Marija, 2021-02-25 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RHOG GEFs activate RHOG
output	[Complex:9014437] RHOG:GTP [plasma membrane] [Homo sapiens] [SimpleEntity:29420] GDP [cytosol]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9714226] Fort, Philippe, 2021-02-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9014446] R-HSA-9014433.2
summation	[Summation:9692977] The following guanine nucleotide exchange factors (GEFs) wer...
(hasEvent)	[Pathway:9013408] RHOG GTPase cycle [Homo sapiens]
(precedingEvent)	[Reaction:9014434] RHOG GAPs stimulate RHOG GTPase activity [Homo sapiens] [Reaction:9014449] RHOG binds effectors at the plasma membrane [Homo sapiens] [BlackBoxEvent:9014454] RHOG translocates to the ER membrane [Homo sapiens]
(replacementInstances)	[_Deleted:9768327] Deletion of instance: 194913
[Change default viewing format]

No pathways have been reviewed or authored by RHOG GEFs activate RHOG (9014433)