Query author contributions in Reactome
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Details on Person Upon stimulation by pathogen-associated inflammatory signals...
| Class:Id | Summation:9013972 |
|---|---|
| _displayName | Upon stimulation by pathogen-associated inflammatory signals... |
| _timestamp | 2017-07-26 06:41:45 |
| created | [InstanceEdit:9013993] Shamovsky, Veronica, 2017-07-26 |
| literatureReference | [LiteratureReference:5362506] Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF |
| text | Upon stimulation by pathogen-associated inflammatory signals TANK associates with TRAF3 which may result in K63-linked ubiquitination of TANK (Gatot JC et al. 2007). How the ubiquitination of TANK contributes to the activation of TBK1 and/or IKKepsilon remains unclear. |
| (summation) | [BlackBoxEvent:9013990] TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TICAM1:TLR3:viral dsRNA [Homo sapiens] |
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No pathways have been reviewed or authored by Upon stimulation by pathogen-associated inflammatory signals... (9013972)
