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Details on Person NICD3 binds RBPJ and MAML in the nucleus

Class:IdReaction:9013631
_displayNameNICD3 binds RBPJ and MAML in the nucleus
_doReleaseTRUE
_timestamp2017-11-02 15:24:27
authored[InstanceEdit:9021699] Orlic-Milacic, Marija, 2017-09-20
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9013639] Orlic-Milacic, Marija, 2017-07-25
edited[InstanceEdit:9015332] Orlic-Milacic, Marija, 2017-08-09
[InstanceEdit:9027527] Orlic-Milacic, Marija, 2017-11-02
goBiologicalProcess[GO_BiologicalProcess:20142] positive regulation of transcription of Notch receptor target
inferredFrom
input[CandidateSet:212357] MAML [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:3008668] RBPJ [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:157928] NICD3 [nucleoplasm] [Homo sapiens]
isChimericFALSE
modified[InstanceEdit:9013642] Orlic-Milacic, Marija, 2017-07-25
[InstanceEdit:9013651] Orlic-Milacic, Marija, 2017-07-25
[InstanceEdit:9015330] Orlic-Milacic, Marija, 2017-08-09
[InstanceEdit:9015339] Orlic-Milacic, Marija, 2017-08-10
[InstanceEdit:9024182] Orlic-Milacic, Marija, 2017-10-02
[InstanceEdit:9027523] Orlic-Milacic, Marija, 2017-11-02
[InstanceEdit:9027526] Orlic-Milacic, Marija, 2017-11-02
[InstanceEdit:9027528] Orlic-Milacic, Marija, 2017-11-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameNICD3 binds RBPJ and MAML in the nucleus
output[Complex:2248837] NOTCH3 coactivator complex [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2017-12-13
reviewed[InstanceEdit:9027525] Haw, Robin, 2017-10-30
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9013640] R-HSA-9013631.2
summation[Summation:9013634] In the nucleus, NICD3 forms a complex with RBPJ (CBF1, CSL) ...
(hasEvent)[Pathway:9013508] NOTCH3 Intracellular Domain Regulates Transcription [Homo sapiens]
(precedingEvent)[BlackBoxEvent:1912415] NOTCH3 gene transcription [Homo sapiens]
[BlackBoxEvent:9013568] HES5 gene expression is stimulated by NOTCH3 [Homo sapiens]
[Reaction:9013652] NOTCH3 coactivator complex binds HES1 gene promoter [Homo sapiens]
[BlackBoxEvent:9014129] HEY1 gene expression is positively regulated by NOTCH3 and STAT1 [Homo sapiens]
[BlackBoxEvent:9014141] HEY2 gene expression is positively regulated by NOTCH3 [Homo sapiens]
[BlackBoxEvent:9016751] FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 [Homo sapiens]
[Reaction:9016916] NOTCH3 coactivator complex binds the PTCRA gene promoter [Homo sapiens]
[BlackBoxEvent:9017398] NOTCH3 coactivator complex binds HEYL gene promoter [Homo sapiens]
[Reaction:9018542] NOTCH3 coactivator complex binds DLGAP5 gene promoter [Homo sapiens]
[Reaction:9021325] NOTCH3 coactivator complex and STAT1 bind HES1 gene promoter [Homo sapiens]
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No pathways have been reviewed or authored by NICD3 binds RBPJ and MAML in the nucleus (9013631)
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