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Details on Person The extracellular matrix is a component of all mammalian tis...

Class:IdSummation:9013587
_displayNameThe extracellular matrix is a component of all mammalian tis...
_timestamp2017-07-25 13:49:54
created[InstanceEdit:9013591] Varusai, Thawfeek, 2017-07-25
modified[InstanceEdit:9013624] Varusai, Thawfeek, 2017-07-25
textThe extracellular matrix is a component of all mammalian tissues, a network consisting largely of the fibrous proteins collagen, elastin and associated-microfibrils, fibronectin and laminins embedded in a viscoelastic gel of anionic proteoglycan polymers. It performs many functions in addition to its structural role; as a major component of the cellular microenvironment it influences cell behaviours such as proliferation, adhesion and migration, and regulates cell differentiation and death (Hynes 2009). Mutations of the extracellular matrix proteins may lead to abnormal cellular functions resulting in pathological conditions.
(summation)[Pathway:9013579] Disorders of extracellular matrix organization [Homo sapiens]
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